Diagnostic Fleet & Capabilities

Advanced Diagnostic Service Catalog

Five specialized clinical divisions powered by world-class automation from Beckman Coulter and dedicated molecular real-time PCR platforms. Delivering reliable, reproducible results with documented methodology and daily multi-rule internal quality controls.

Division I · Beckman Coulter AU480 · DxC 700 AU · ISE Potentiometry

Clinical Chemistry & Metabolic Profiling

TAT: 2–6 hours (STAT: < 45 min)
Division Mandate & Scientific Scope

Our Clinical Chemistry department is anchored by two automated clinical chemistry analyzers from Beckman Coulter: the high-throughput DxC 700 AU and the versatile AU480. Combining precision spectrophotometry and Ion-Selective Electrode (ISE) potentiometry, the platform delivers quantitative analysis for organ function, critical electrolyte balance, and glycemic control.

Core Methodologies
Dual-Beam SpectrophotometryIon-Selective Electrode (ISE) PotentiometryWhole-Blood Enzymatic HbA1cAutomated Clot Detection & Liquid Level Sensing

Featured Instrumentation & Equipment Fleet

Beckman Coulter DxC 700 AU

Beckman Coulter
High-Throughput Core Chemistry Analyzer
Capacity: Up to 1,200 tests/hour with ISE (800 photometric tests/hr); 150 routine samples + 22 dedicated STAT priority positions.
  • Direct whole-blood HbA1c testing for diabetes screening and monitoring
  • Ultra-low sample volume: 1–25 µL per test to conserve pediatric and geriatric specimens
  • Real-time automated reflex testing, repeat dilutions, and continuous reagent loading

Beckman Coulter AU480

Beckman Coulter
Automated Clinical Chemistry & Rapid STAT Analyzer
Capacity: Up to 800 tests/hour with ISE (400 photometric tests/hr); 80-rack routine capacity + 22 STAT samples.
  • High analytical precision across liver, renal, and cardiac enzyme profiles
  • Automated liquid-level sensing and specimen integrity verification
  • Primary tube sampling with internal barcode tracking

Clinical Assay Menu & Test Panels

Metabolic & Glycemic Monitoring

  • Fasting Blood Glucose
  • Whole-Blood HbA1c (Glycated Hemoglobin)
  • Uric Acid
  • Serum Lactate

Renal Function Profiles

  • Urea / Blood Urea Nitrogen (BUN)
  • Serum Creatinine
  • BUN/Creatinine Ratio
  • Estimated GFR (eGFR)

Liver Function & Hepatic Enzymes

  • AST (SGOT)
  • ALT (SGPT)
  • Alkaline Phosphatase (ALP)
  • Total Bilirubin
  • Direct Bilirubin
  • Total Protein & Albumin
  • Albumin/Globulin Ratio

Lipid & Cardiovascular Risk

  • Total Cholesterol
  • HDL Cholesterol
  • LDL Cholesterol (Calculated/Direct)
  • Triglycerides
  • Cardiac Risk Ratios

Electrolyte Balance (ISE)

  • Sodium (Na+)
  • Potassium (K+)
  • Chloride (Cl-)
  • Serum Calcium & Phosphorus
Specimen & Collection Protocol

Serum separator tube (Gold top / SST) or Lithium Heparin (Green top); EDTA whole blood for HbA1c. Minimum 2–3 mL.

Analytical Advantage
  • STAT Emergency turnaround with priority analytical bypass within 45 minutes
  • Micro-sampling technology (1–25 µL) ideal for pediatric and neonate collections
  • Automated secondary dilution and out-of-range verification without technician hands-on
Division II · DxH 900 · DxI 800 · Access 2 · Chemiluminescence

Hematology, Coagulation & Advanced Immunoassays

TAT: 1–4 hours (STAT CBC: < 30 min)
Division Mandate & Scientific Scope

A comprehensive diagnostic division combining flagship cellular hematology and automated chemiluminescent immunoassay. Powered by the Beckman Coulter DxH 900 with VCS 360 3D laser technology, alongside the UniCel DxI 800 and Access 2 immunoassay analyzers, providing deep clinical coverage across hematology, endocrinology, cardiology, oncology, and infectious serology.

Core Methodologies
VCS 360 3D Multi-Angle Laser Cellular AnalysisEnhanced Coulter Principle (High-Resolution Impedance)DataFusion Multi-Sensor Cellular AlgorithmsChemiluminescent Detection & Magnetic Particle Separation

Featured Instrumentation & Equipment Fleet

Beckman Coulter DxH 900

Beckman Coulter
Flagship Fully Automated Cellular Hematology Analyzer
Capacity: Up to 100 samples/hour with continuous automated rack feeding and STAT urgent sample interruption.
  • VCS 360 interrogates white blood cells in their near-native state using Volume, Conductivity, and 5-Angle Multi-Laser Light Scatter (0°, 10°, 20°, 28°, 43°)
  • DataFusion multi-dimensional sensor analysis drastically reduces unnecessary manual slide review rates while flagging abnormal blasts and immature granulocytes
  • Direct automated Reticulocyte count (RET%, RET#, IRF) and Nucleated Red Blood Cells (NRBC) without separate reflex gates

Beckman Coulter UniCel DxI 800

Beckman Coulter
High-Throughput Chemiluminescent Immunoassay Platform
Capacity: Up to 400 tests/hour; 120 specimens with continuous loading and up to 50 refrigerated onboard reagent packs.
  • Walkaway operation with automatic reflex, repeat, and dilution algorithms
  • Broad clinical menu across cardiac, tumor, endocrine, and viral markers
  • STAT sample prioritization with zero disruption to active batch runs

Beckman Coulter Access 2

Beckman Coulter
Compact Benchtop Automated Immunoassay Analyzer
Capacity: Up to 100 tests/hour; 60 samples with up to 24 onboard assays.
  • Identical analytical chemistry and assay protocols to the high-throughput DxI 800 for seamless cross-instrument consistency
  • Zero dedicated external water system requirement, maximizing operational reliability

Clinical Assay Menu & Test Panels

Complete Hematology & Cytometry (DxH 900)

  • Complete Blood Count (CBC) with RBC Indices (MCV, MCH, MCHC, RDW)
  • 5-Part Differential Count (Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils)
  • Automated Reticulocyte Analysis (RET%, RET#, Immature Reticulocyte Fraction - IRF)
  • Automated Nucleated Red Blood Cells (NRBC)
  • Selected Body Fluid Cytometry (CSF, Pleural, Peritoneal, Synovial cell counts)

Cardiac Biomarkers (DxI 800 / Access 2)

  • High-Sensitivity Troponin I (hs-Troponin I)
  • Troponin I
  • CK-MB Mass
  • BNP (B-type Natriuretic Peptide)

Thyroid & Endocrine Function

  • TSH (3rd Generation Ultrasensitive)
  • Free T4
  • Free T3
  • TPO Antibody (Anti-Thyroid Peroxidase)

Reproductive & Fertility Health

  • Anti-Müllerian Hormone (AMH)
  • Quantitative β-hCG
  • FSH
  • LH
  • Estradiol (E2)
  • Progesterone
  • Prolactin

Anemia & Mineral Metabolism

  • Ferritin
  • Vitamin B12
  • Folate
  • Erythropoietin (EPO)
  • 25-OH Vitamin D
  • Intact PTH (Parathyroid Hormone)
  • Ostase (Bone ALP)

Tumor Markers & Oncology

  • CEA
  • CA 125 (Ovarian)
  • CA 19-9 (Gastrointestinal)
  • CA 15-3 (Breast)
  • Total PSA & Free PSA
  • p2PSA & Prostate Health Index (phi)

Infectious Serology & Blood Viruses

  • HIV 4th Gen Antigen/Antibody Combo
  • HBsAg & HBsAb
  • Anti-HBc Total
  • Anti-HCV
  • Rubella (IgG/IgM)
  • Toxoplasma (IgG/IgM)
  • Cytomegalovirus (CMV IgG/IgM)

Coagulation & Hemostasis

  • Prothrombin Time / INR (PT/INR)
  • Activated Partial Thromboplastin Time (APTT)
  • D-Dimer (Quantitative)
Specimen & Collection Protocol

EDTA tube (Purple top) for CBC & Reticulocytes; Citrate tube (Blue top) for Coagulation; Plain / SST tube (Gold top) for Immunoassays.

Analytical Advantage
  • Near-native cell state measurement via VCS 360 to prevent osmotic cellular distortion
  • Prostate Health Index (phi) incorporating [-2]proPSA for precise prostate risk stratification
  • High-Sensitivity Troponin I with micro-concentration precision for early acute coronary assessment
Division III · Real-Time PCR · High-Risk HPV Genotyping · GeneXpert MTB/RIF

Molecular Diagnostics & HPV Genotyping

TAT: 4–24 hours
Division Mandate & Scientific Scope

Operating under strict BSL-2 molecular biocontainment with unidirectional workflow zones (reagent prep, extraction, amplification/detection). Our molecular division features real-time PCR platforms and GeneXpert automated cartridge systems, with specialized protocols for High-Risk Human Papillomavirus (HPV) Genotyping, quantitative viral load monitoring, and pathogen resistance.

Core Methodologies
TaqMan Probe Real-Time Fluorogenic PCRHigh-Risk HPV Oncogenic GenotypingAutomated Magnetic Bead Nucleic Acid ExtractionClosed-System Microfluidic Amplification (GeneXpert®)

Featured Instrumentation & Equipment Fleet

Real-Time PCR & HPV Genotyping Platform

Beckman Coulter
Multiplex Fluorescence Real-Time Thermal Cycler
Capacity: High-throughput 96-well amplification with multi-channel fluorescence detection.
  • High-Risk HPV Genotyping Test: Differentiates oncogenic high-risk HPV types (including HPV 16 and HPV 18) linked directly to cervical intraepithelial neoplasia and cervical cancer
  • Enables early risk assessment and proactive triage before cervical abnormalities progress
  • Supports outpatient clinics, gynecological screening, and hospital referral programs

GeneXpert® Automated Molecular Diagnostic System

Beckman Coulter
Closed-Cartridge Nucleic Acid Amplification
Capacity: Random-access on-demand processing with automated hands-off extraction and PCR.
  • GeneXpert MTB/RIF®: Direct identification of Mycobacterium tuberculosis complex and simultaneous rifampicin resistance detection in under 2 hours
  • Closed biocontainment cartridge design preventing amplicon cross-contamination

Clinical Assay Menu & Test Panels

Cervical Cancer Screening & Prevention

  • High-Risk HPV Genotyping Test (Identification of HPV 16, 18, and grouped high-risk oncogenic types)
  • Early Risk Assessment & Clinical Triage Screening
  • Reflex HPV DNA Confirmation Following Abnormal Cytology

Tuberculosis & Antimicrobial Resistance

  • GeneXpert MTB/RIF® — Mycobacterium tuberculosis Detection
  • Rifampicin Resistance Mutation Profiling

Quantitative Viral Load Monitoring

  • HIV-1 RNA Quantitative Viral Load
  • Hepatitis B Virus (HBV-DNA) Quantitative Real-Time PCR
  • Hepatitis C Virus (HCV-RNA) Quantitative Real-Time PCR

Respiratory & Special Pathogens

  • SARS-CoV-2 RT-PCR (Multiplex Targets)
  • Herpes Simplex Virus (HSV 1/2) PCR
Specimen & Collection Protocol

Cervical swab in liquid-based cytology medium for HPV; EDTA whole blood/plasma for viral loads; Sputum or sterile body fluid in sterile container for GeneXpert MTB.

Analytical Advantage
  • Oncogenic HPV risk stratification: "Know your status, protect your future" early detection initiative
  • Strict 3-room physical separation (Reagent Master Mix Room → Extraction Room → Amplification Room) guaranteeing zero contamination
  • Reportable linear dynamic range for viral loads spanning 20 to 10,000,000 copies/mL
Division IV · Surgical Biopsies · FNAC · Liquid-Based Cytology

Pathology & Cytology Services

TAT: 48–72 hours
Division Mandate & Scientific Scope

The Pathology and Cytology division provides comprehensive surgical tissue grossing, paraffin embedding, microtomy, special staining, and cytological evaluation. Every specimen is examined and signed out by certified pathologists with formal multi-tier diagnostic reviews for neoplastic and complex cases.

Core Methodologies
Vacuum Paraffin InfiltrationThin-Layer Liquid-Based Cytology (LBC)Special Histochemical Stains (PAS, Giemsa, Ziehl-Neelsen)Dual Pathologist Microscopic Sign-Off

Featured Instrumentation & Equipment Fleet

Automated Tissue Processor & Microtomy Suite

Beckman Coulter
Histopathology Tissue Processing & Sectioning Bench
Capacity: Enclosed vacuum tissue processing for consistent, standardized dehydration, clearing, and paraffin infiltration.
  • Uniform 3–4 micron ribbon sectioning for optimal nuclear and cytoplasmic morphology
  • Standardized Hematoxylin & Eosin (H&E) staining protocols with strict pH control

Clinical Assay Menu & Test Panels

Surgical Histopathology

  • Surgical Biopsy — Gross Description, Microscopic Evaluation & Pathologist Report
  • Endoscopic & Punch Biopsy Evaluations
  • Resection Margins & Tumor Node Staging

Exfoliative & Aspiration Cytology

  • Fine Needle Aspiration Cytology (FNAC) with Rapid On-Site Evaluation (ROSE)
  • Liquid-Based Cervical Cytology (Thin-layer Pap Smear)
  • Pleural, Peritoneal, and Pericardial Fluid Cytology
  • Urine Cytology for Urothelial Malignancy
  • Bone Marrow Aspirate Cytology & Iron Stain Evaluation
Specimen & Collection Protocol

Biopsy tissue in 10% neutral buffered formalin (container volume at least 10x tissue volume). FNAC air-dried and alcohol-fixed slides with accompanying clinical history.

Analytical Advantage
  • Secondary independent pathologist review for all malignant diagnoses
  • Integration with Molecular Division for reflex HPV genotyping on abnormal cervical cytology
Division V · IRB Studies · EQA Proficiency · Method Validation

Research Support & Quality Reference Hub

TAT: Scheduled by institutional agreement
Division Mandate & Scientific Scope

Serving both ECUSTA’s academic community and external collaborative investigators, this division offers specialized analytical support for clinical trials, thesis research, and laboratory method validation. The facility actively participates in national and regional External Quality Assessment (EQA) proficiency testing.

Core Methodologies
Westgard Multi-Rule Statistical Quality EvaluationCalibrated Bio-Banking Storage (-80°C & -20°C)National EQA Proficiency Survey BenchmarkingMethod Verification & Reference Interval Analysis

Featured Instrumentation & Equipment Fleet

Quality Reference Suite & Analytical Controls

Beckman Coulter
Proficiency Testing & Research Specimen Platform
Capacity: Deep-freezer bio-banking (-80°C and -20°C calibrated storage) with continuous temperature telemetry.
  • Direct analytical support for undergraduate and postgraduate MLT thesis studies
  • Contract research processing for university and hospital epidemiological investigations

Clinical Assay Menu & Test Panels

Academic & Clinical Research Services

  • IRB-Approved Thesis & Dissertation Specimen Analysis
  • Epidemiological Biomarker Testing for Public Health Surveys
  • Instrument Method Validation & Comparative Precision Studies
  • Local Population Reference Interval Establishment
  • Laboratory Quality Management System (LQMS) Training Bench
Specimen & Collection Protocol

Institutional Review Board (IRB) approval letter and formalized study protocol required for all research specimen submissions.

Analytical Advantage
  • Strict segregation between academic research runs and live hospital diagnostic workflows
  • Comprehensive analytical data export with raw photometric, scatter, and cycle threshold (Ct) logs for researchers

Need Testing Not Listed in This Catalog?

Our senior clinical coordinators can evaluate assay feasibility, coordinate custom test panels, or arrange structured reference routing through our established national healthcare network.